Ingredy

5-Hydroxytryptophan

5-HTPOxidized tryptophanTryptophan metabolite

Mood Enhancer

5-HTP is a chemical that your body makes from the amino acid tryptophan. It helps make serotonin, a brain chemical that can improve your mood.

Moderate Concern

Source: EFSA assessment

The concern is that high doses may interact with certain medications, such as antidepressants, and cause side effects like nausea and diarrhea.

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r/NooTopics

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Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis.

Javelle F, Lampit A, Bloch W

2020

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Last updated: May 16, 2026